If you’re prone to sweating in hot environments, then wipes can be useful to decrease sweat build-up in the vaginal area, says Dr. Shepherd. However, if you’re prone to yeast infections, currently have a discharge that is abnormal, or any sores or lesions, it is best not to use wipes at all. In fact, all you need to stay clean is mild soap and water, Professors says, and that in general there is no way to confirm a wipe is “safe” to use. Lastly, don’t forget that constant use of wipes can disrupt the vagina's natural pH and that wipes do not treat or prevent STIs or pregnancy.